Background: The pregnancy is the state of carrying a developing embryo or fetus within female body1. Preeclampsia affects 3-5% of pregnancies. Ten million women develop preeclampsia each year around the world. Placental ischemia and inflammation occur due to impaired trophoblastic invasion in uterine spiral artery. Hs-CRP is the marker of inflammation
Aim: To evaluate the predidctive value of Hs-CRP in Preeclampsia.
Materials And Methods: A case control study of 60 subjects (30 preeclamptic primigravida and 30 age matched healthy pregnancies). Hs-CRP by immunoturbidimetric method.
Results: 30 women in preeclamptic compared with 30 normal pregnant with similar age and period of gestation . The mean SBP of the cases and controls are 157.7 mm of Hg and 113.6 mm of Hg with significant p value < 0.0001. The mean DBPin cases and controls is 101.4 mm of Hg and 77.47 mm og Hg with significant p< 0.0001. The hs-CRP levels in cases is 1.08 ± 0.79 mg/L, when compared to controls 0.23 ± 0.19 mg/L with p <0. Hs-CRP has significant cut off point of >0.26 with sensitivity of 90 and specificity of 73.33 that is if value of Hs-CRP >0.26 then, there is significantly high risk of disease.
Impact Factor
2022: 6.012
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