Chronic periodontitis is defined as "an infectious disease resulting in inflammation within the supporting tissues of the teeth, progressive attachment loss, and bone loss."The primary aim to treat periodontitis is the elimination of specific periodontal pathogens with adjunct use of local and systemic antibiotics along with scaling and root planing. Natural extracts such as lemongrass recently become very popular because unwanted side effects and resistance of microorganisms are seen with antibiotics. Medicinal plant usagein phytosciences have been developed. This leads to the choice of using antimicrobial therapy. Cymbopogon citratus, (lemongrass) is used in the treatment of periodontitis. Chlorhexidine acts as the “Gold standard” agent for chemical plaque control. Antiseptic activity of chlorhexidine helps in the control of plaque. This study evaluates the efficacy of local drug delivery of lemongrass gel in comparsion with the chlorhexidine gel in the treatment of chronic periodontitis.