Introduction: During chemotherapy for treatment of cancer lead to some degree of electrolyte derangement, but exact frequency and type of electrolyte imbalances has not been well documented. Therefore we wanted to conduct this study.
Objective: To see frequency of electrolyte imbalances among cancer patients during Chemotherapy.
Material and methods: This is a cross sectional observational study which was conducted from 1st April 2016 to 30 Mar 2017inthe Department of Oncology, Jinnah Postgraduate Medical Centre, Karachi after obtaining approval from institutional ethical review committee. 256 cancer patients, age range 18-70 years who received single or combination chemotherapy were included.
Results: In the total of 256 cancer patients divided into 12 groups depending upon chemotherapeutic regimen, the overall incidence of hyponatremia was 52.7%, for hypokalemia was 42.2%, for hypochloremia was 14.8% and for hypomagnesaemia was 10.2%. The mean age in all groups ranged from 27.42±8.92 years to 49.50±11.71 years. (P-value=0.001). The mean weight in all groups ranged from 50.10±18.57 kg to 64.58±13.95 kg. (P-value=0.03). The mean chemotherapy days in all groups ranged from 4.97±1.44 days to 8.52±3.70 days. (P-value=0.001).
Conclusion: Our study showed that electrolyte imbalances common during chemotherapy and medical oncologist should monitor their levels while on chemotherapy.
Impact Factor
2022: 6.012
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