Efficacy of 1% atorvastatin dentifrice as an adjunct to non surgical periodontal therapy in chronic periodontitis

Aim: To clinically evaluate the effect of 1% atorvastatin dentifrice in adjunct to scaling and root planing in Chronic Periodontitis and to compare its efficacy with placebo dentifrice
Materials and Methods: 70 Chronic Periodontitis patients aged between 30 to 60 years with minimum of 14 teeth present were selected from OPD of Department of Periodontology, FDS, RUAS, Bangalore for the study. The study population was divided into two groups. Group A (n=35) 1% atorvastatin dentifrice in adjunct to NSPT. Group B (n=35) placebo dentifrice in adjunct to NSPT.Clinical Parameters (GI,PI,PPD,CAL) were assessed at baseline and 1 month.
Result: Statistically significant improvement was seen in clinical parameters ( GI, PI, PPD, CAL) at one month in both the groups. On intergroup comparison , statistically significant difference was noted in values of GI,PI, PPD,CAL between Group A and Group B at 1 month wherein Group A demonstrated better results when compared to Group B
Conclusion: 1% Atorvastatin dentifrice used as an adjunct to NSPT showed better clinical efficacy than placebo group in Chronic Periodontitis patients.