Background: Periodontal health has become an integral part of the oral health. Various treatment modalities have been evolved to maintain the periodontal health intact. The success rate of these periodontal treatment modalities can be questionable due to the commonly occurring post-operative infections. Hence emerged the attempt of using silver nanoparticles in dental materials and its antimicrobial effect in dentistry.
Review Results: Numerous studies revealed its significant antimicrobial and antiadhesive property and have also explained its activity in periodontal procedures by impregnating in membranes, scaffolds and implants. Unfortunately, very limited clinical trials have been conducted to prove its efficacy and to state its side effects.
Discussion: Various mechanisms have been contributed towards the antibacterial effect of silver nanoparticles. Available literatures suggested the prevention of bacterial adhesion, termination of mitosis, production of reactive oxygen species and disruption of cell membrane as the possible mechanisms involved in exhibiting antibacterial action.
Conclusion: Though silver nanoparticles have been used actively in the field of medicine for past few decades, worldwide various studies are still in process to prove its efficacy in dentistry.
Clinical Significance: With the limited clinical trials and enormous in vitro studies, silver nanoparticles were considered to be a potent antimicrobial agent reducing post-operative infections in periodontal surgeries.