Aim: To evaluate the effectiveness of platelet-rich fibrin (PRF) in preventing alveolar osteitis (AO) development following trans alveolar extractions.
Materials and Methods: The present study was done on 60 patients on an outpatient basis in the Department of Oral and Maxillofacial surgery in Rajarajeswari dental college and hospital, Bangalore. Patients indicated for trans alveolar extraction were selected for the study. Following extraction, platelet rich fibrin prepared from patients own blood was placed in the extraction socket of the study group. The patients were assessed for postoperatively pain, halitosis and presence of healthy granulation tissue. On the 3rd and 7th postoperative day.
Results: All the local signs and symptoms were mild to moderate and subsided in normal course of time. Pain was less in study group compared to control group. Soft tissue healing was better in the study group. Socket healing after trans alveolar extraction was better and faster in the study group.
Conclusion: The study showed that autologous PRF is biocompatible and has significantly improved soft tissue healing and thus preventing the incidence of alveolar osteitis. However, a more elaborate study with a larger number of clinical cases is very much essential to be more conclusive regarding its efficacy.