Effect of ageing on liver function

INTRODUCTION: Ageing occurs at many levels –social, psychological, physiological, morphological, cellular and molecular levels. Change in protein metabolism could be the major result of age related difference and would have far reaching effects. In general protein synthesis declines with age and turnover also declines. Liver plays a major role in protein synthesis and degradation. OBJECTIVES: To find the effect of ageing on liver functions. METHODS: 120 healthy subjects between the age group 21 and 90 yrs were recruited for the study. They were divided into seven groups depending on the age. Their liver functions (SGOT, SGPT, ALP, B were estimated by autoanalyser and was statistically analysed. RESULT: They were no statistical significance as the age advance in the liver function. CONCLUSION: The study convincingly proves that there is no adverse effect on liver due to ageing.