Diphtheria, pertussis and tetanus vaccine (dpt) induced seizures: a suspected case in a pediatric patient

A 4 months old male patient was admitted in the hospital with the chief complaint of 2 episodes of generalised tonic clonic seizures, raised body temperature and altered sensorium after the first dose of DPT vaccine under routine immunisation schedule. DPT vaccine induced seizures diagnosis was made and treated. Pertussis component of the DPT vaccine is mainly responsible for neurologic reactions and the relationship between DPT vaccine and seizures was shown as a probable ADR. The patient was improved on 2nd day with the treatment and finally recovered and discharged on 4th day. Patient was followed up after a period of 3months and found to have no neurological defects.