The upflow anaerobic sludge blanket reactor seeded with endemic consortia created from municipal wastewater isolates was utilized to treat raw domestic wastewater of medium strength. The UASB reactor required a time of 90 days to start up. The execution of reactor to treat municipal wastewater was upgraded with an expansion in the sludge age, pH/Salinity and Hydraulic Retention Time. At early sludge age (60 days), chemical oxygen demand (COD) and biochemical oxygen demand (BOD) expulsion by the reactor was in the scope of 59- 71%. Be that as it may, chemical oxygen demand (COD) and biochemical oxygen demand (BOD) evacuation proficiency of the reactors hoisted to the scope of 79- 81% at sludge age of 150 days. To put it plainly, general execution of reactor was ideal at sludge age extending from 120 to 150 days, pH 7 and salinity 1%(w/v). At Hydraulic Retention Time (HRT) of 7.5 hrs the chemical oxygen demand (COD), suspended solids (TSS) and sulfate evacuation proficiency of UASB reactor achieved 81%, 75% and 76%, separately. The rate of evacuation of these parameters be that as it may, bit by bit declined with expanding Hydraulic Retention Time. The UASB innovation gives a minimal effort framework to the immediate treatment of municipal wastewater and can be connected in smallfraternity.