A convenient synthesis and spectral studies of n, n-bis ((2-chlorothiazole-5-yl) methyl)-6-methylbenzo (d)thiazol-2-amine

Author: 
Aakash Kumar, Manoj Kumar Tyagi, Mukul Chauhan

4-methylaniline in chlorobenzene reacted with sulphuric acid, sodium thiocyanate and sulfuryl chloride to give 2-amino-6-methyl benzothiazole. This 2-amino-6-methyl benzothiazole was later further reacted with 2-chloro-5-chloromethylthiazole in the presence of N, N'-dimethyl formamide (DMF) and anhydrous potassium carbonate (K2CO3) to afford N,N-bis((2-chlorothiazole-5-yl)methyl)-6-methylbenzo(d)thiazol-2-amine.

Download PDF: 
DOI: 
http://dx.doi.org/10.24327/ijcar.2018.12608.2222
Select Volume: 
Volume7