A comparitive study of intrathecal fentanyl and dexmedetomidine as adjuviants to bupivacaine

Author: 
Mohd Heifzur Rahman, Chander Bukya and Geetha Channaram

Aim of the Study: To study the efficacy of Intrathecal Fentanyl and Dexmedetomidine with Bupivacaine for infra umbilical surgeries. Material & Methods: A prospective randomized double blinded comparative study has been conducted in 100 patients belonging to ASA physical status I & II of both sexes were divided into two groups of 50 each. Results: Time from injection to highest sensory level and Onset of Bromage 3 was similar in both groups. Time from injection to T10 sensory level was significantly shorter in Group D (p<0.001), and Time for regression to Bromage 0 was significantly longer in group D (p<0.001). Intraoperatively both groups remained haemodynamically stable. Incidence of bradycardia was more in Group D and incidence of pruritus was more in Group F though it was not statistically significant (p=0.402). Intraoperative sedation was higher in Group D (p<0.001) and post operatively Visual analogue scores were significantly lower with group D (p<0.001). Conclusion: Dexmedetomidine appears to be an attractive adjuvant to intrathecal bupivacaine than Fentanyl as there is significantly longer duration of motor block, additional benefits of intraoperative sedation and decreased analgesic requirement in the post-operative period.

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DOI: 
http://dx.doi.org/10.24327/ijcar.2022.1308.0291
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