Background: Various studies in the past have established the role of clonidine and nalbuphine as an adjuvant to local anaesthetic, not many studies have compared the efficacy between them. Aim: The present study has been undertaken to compare intrathecal nalbuphine and clonidine as adjuvants to bupivacaine in lower abdominal and lower limb surgeries. Methods: In this prospective, double blinded, randomized, and comparative study, a total of sixty patients each of American Society of Anaesthesiologists physical status Classes I and II undergoing lower abdominal and lower limb surgeries under subarachanoid block were randomly divided into two groups. In group ‘N’ received 1.6mg of Nalbuphine and in group ‘C’ recieved 30 micrograms (0.2ml) with 3ml 0.5% hyperbaric bupivacaine diluted with normal saline to make a total volume of 3.5ml intrathecally. The onset time and duration of sensory and motor block, duration of block, duration of analgesia, postoperative analgesic requirement, sedation score, haemodynamic parameters and side effects were noted. Results: In our study we found that that the onset of sensory and complete motor block was faster in the Nalbuphine group as compared to the clonidine group. The total duration of sensory and motor block were significantly prolonged in the clonidine group. The duration of analgesia was longer in the patients who received clonidine. Conclusion: Intrathecal clonidine is associated with pronlonged motor blockade, less post operative analgesic requirement as compared to nalbuphine.
Impact Factor
2022: 6.012
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