Comparative study of safety and efficacy of glycolic acid peel (70%) and trichloroacetic acid peel (20%) in melasma patient

Author: 
Sudhir Kumar Singh., Yatendra Singh Chahar., Karamvir Singh., Sudha Chaudhary and Isha singh

Background: Melasma is a symmetric progressive hyperpigmentation of the facial skin. Glycolic and TCA peel are the popular peeling agents used and more commonly peeling agents for superficial and medium depth peels.
Objectives: To compare the safety and efficacy of glycolic acid (70%) and TCA peel (20%) in melasma patient.
Materials and Methods: 80 patients as per inclusion criteria attending in the skin OPDwere selected and randomly divided into 2 groups A and B, MASI score was calculated and were subjected to wood’s light to determine the melasma type. The peels were applied after every 3 weeks and 6 sessions were done.
Results: There was statistically significant difference between the two peels as the percentage change in the initial and final MASI scores in Glycolic acid peel is 59% decrease and whereas it was 43% decrease in case of TCA peel.
Conclusions: Our study proves the efficacy of glycolic acid (70%) peel over TCA(20 %) in the melasma patients. Side effects especially post peel cracking and post inflammatory hyperpigmentation were more with TCA peel.

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DOI: 
http://dx.doi.org/10.24327/ijcar.2022.463.0102
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