Clinical types of oral lichen planus and their co-relation with serum t3, t4, tsh level

Aims and Objectives: To determine the co-relation between the types of oral lichen planus, and serum T3,T4, TSH level. This study also aims at age and sex related serum T3,T4,TSH level and types of Oral lichen planus.
Materials and Method: The whole blood sample(5ml) will be collected from oral lichen planus patient diagnosed by clinical and histopathology examination. The serum of same patients will be analysed for levels of thyroid hormones (free triiodothyronine T3, free thyroxineT4 and thyroid-stimulating hormoneTSH),T3,T4 value is determined by electro-chemiluminescence immunoassay analyzer (ECLIA) however TSH value is determined by ultrasensitive enhanced chemiluminescence(Ultra sensitive 4th generation Chemiflex).
Results: Reticular oral lichen planus(50%) is most common in study population while bullous (6.7%) type of oral lichen planus is least common.Oral lichen planus is most commonly found on right and left buccal mucosa(53.3%) however left buccal mucosa (3.3%) is least common site .The serum T3,T4 and TSH level varies irrespective of clinical subtypes of oral lichen planus(p value<.05).The occurrence of clinical subtypes of oral lichen planus is independent of age and sex (P value<.05%).Theserum T3, T4 and TSH level is statistically not significant in male and females and age groups(P value<.05%).
Conclusion: Serum T3, T4, and TSH level is independent of clinical subtypes of Oral lichen planus i.e. the serum level of T3, T4, and TSH is not specific to particular type of Oral lichen planus. It varies from type to type of oral lichen planus.