Clinical profile of sickle cell disease patients in south rajasthan

Background: Sickle cell disease is a major health problem among the tribal population which leads to varied complications and even resulting in premature death. Probable estimate of this condition in Southern Rajasthan is quite high. Authors aim to determine the spectrum of manifestations of the Sickle Cell Disease patients. Objective: To study the clinical manifestations of Sickle cell disease patients visiting a tertiary care hospital at Udaipur, Rajasthan and to compare between manifestations of homozygous state (HbSS) v/s Sickle beta thalassemia patients. Study Design: This study was a hospital based observational prospective study. Participants: 38 patients with sickle cell disease were included in this study. Methods: Present study was conducted at Center of Excellence for Sickle cell Disease, RNT Medical College, Udaipur, Rajasthan. Patients with Sickle Cell Disease visiting our center were thoroughly examined and investigated along with scrutiny of past medical records. Results: Conclusion: This study shows that sickle cell disease leads to various complications leading to a significant impact on quality of life. There is a need for more extensive studies over the subject in this region.