Introduction and Objectives: Hepatitis E virus causes acute viral hepatitis. Being waterborne infection, Monsoon season is associated with high risk of epidemics Monsoon season is associated with high risk of epidemics.Our study aimed to evaluate the clinical profile and predictors of severity in patients of viral hepatitis epidemic in Jaipur during May 2014 to Jan 2015. Cases evaluated in the study were both Index cases and referred cases from epidemic area, for worsening of jaundice and other complications.
Material and Method: This study was conducted on 64 patients presenting with acute hepatitis in Metro MAS hospital over period of 9 months from May 2014 to Jan 2015. A detailed history of each patient was recorded, including travel history, blood transfusion, food and water intake from outside sources. The diagnosis of acute viral hepatitis was based on accepted clinical, biochemical and serological criteria.
Results: In present study, viral hepatitis was predominantly seen in middle age. Males (81%) were predominantly affected. Out of female (19%) patients, 2 were pregnant. Maximum patients presented with jaundice (90%), followed by nausea and vomiting (60%), fever (30%) and abdominal pain (13%). Most common sign was icterus followed by tender hepatomegaly (28%). Virology study showed 40 cases positive for HEV, 3 cases for HBV and 5 cases were positive for HAV. In 3 cases, RFT was raised above 2mg/dl out of which 1 required hemodialyses. 8 cases were found with deranged prothrombin time and 6 received FFP in view of active bleeding. No Mortality was seen in our study.
Conclusion: Our study suggests that the outbreaks in Jaipur district were due to Hepatitis E virus. Jaundice was the most common presenting feature followed by vomiting; fever and pain.Early presentation and judicious treatment can prevent mortality. Majority of cases were cured with supportive treatment.
Impact Factor
2022: 6.012
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