The platelets play a vital role in the process of healing and are known to release several growth factors. The growth factors present in platelets guide the regenerating cells to stimulate regeneration of bone and maturation of soft tissue. Various platelet aggregates such as PRGF, PRP, and PRF can be used as an adjunct in wound healing, correction of osseous defects, apexification, revascularization, etc. This review article focuses on the different types of platelet concentrates and their clinical application in various fields of Dentistry in a wide range of treatment modalities.