Nowadays, nanoparticles has revolutionized the concept of drug targeting system and there are various nanoparticle available around us and from that one of them is Chitosan. Chitosan is a mucopolysacharide and it is the biproduct of exoskeletons in crustaceans. The chitosan nanoparticles is considered as a safe material due to its biocompatibility, better stability, low toxicity, simple preparation methods and it act as a very good adjuvant for the process of drug delivery and thusact as a valuablevehicle for the delivery of drugs in the present era. The present review highlights about various aspects of chitosan and how it holds promise as a suitable material for biomedical applications. The predicted aspects of chitosan’s targeting area in human has been discussed here for the first time.