Background: Caudal analgesia is frequently used as an paediatric anaesthesia. It is a safe and reliable technique that can be used with general anesthesia for perioperative analgesia in patients undergoing abdominal surgeries. Clonidine is an alpha2-adrenergic agonist, used for analgesic effects in different doses with 0.25% bupivacaine. The aim of the study to evaluate quality and duration of analgesia with various dosages of clonidine with bupivacaine as an adjuvant.
Method: A totalninetypaediatric patients were comprises to three groups(30 each group): caudal analgesia with 1 ml/kg of 0.25% bupivacaine in normal saline (group I), 1 ml/kg of 0.25% bupivacaine with 0.8 μg/kg of clonidine (group II) and 1 ml/kg of 0.25% bupivacaine with 1.0 μg/kg of clonidine (group III)undergoing lower abdominal surgery. FLACC scale was used for assessment of post-operative pain.
Result: At 15 min. after extubation the mean score were significantly lower in group III (0.89±0.370 as compared to group II (1.30±0.35) and group I (1.97±0.43). The mean duration of 1st time requirement of analgesia in the group III was significantly longer as compared to group II and group I. Moreover, the number of patients requiring rescue anaesthesia one dose or two dose were comparable in between groups.
Conclusion: our study showed that the clonidine 1 μg/kg with 0.25% bupivacaine for caudal analgesia was prolongs the duration of analgesia and lower the requirement of rescue analgesia.
Impact Factor
2022: 6.012
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