Resume: Acanthamoeba keratitis (A.K.) is a relativety uncommon but potentatially devastating coreal infection. It is usually missed.
The following case report describes a patient who developed radial keratitis transformed during evolution into nummular keratitis. The corneal scraping was negative. This made the diagnosis difficult.
An etiological investigation revealed that he had been hospitalized two months previously for gastroenteritis. The isolation of the entamoeba histolytica in the stool and the good evolution under antiamibian treatment are in favor of amoebic keratitis.
Clinical history, radial perineuritis and effecience of treatment are the capital items to evocate diagnosis of this clinical entity.