Regrettably, a pregnancy loss occurs because of various reasons. It causes an extraordinary outpouring grief, confusion, and fear. Recurrent pregnancy loss (RPL) causing anxiety, sorrow, pain, and upsetting. Miscarriage is the spontaneous loss of a pregnancy before 20th week. About 15 -20 % of known pregnancies end in miscarriage. Most miscarriages occur because the fetus is not developing normally. Problems with the baby's genes or chromosomes typically result from errors that occur by chance as the embryo divides and grows. In blighted ovum, when a fertilized egg develops a placenta and membrane, but no embryo. Intrauterine fetal demise occurs due to genetic abnormalities of the embryo. Gestational trophoblastic disease or molar pregnancy, the placenta develops into the fast-growing mass of cysts in the uterus, which may or may not contain an embryo