Background: NAFLD is a clinicopathologic syndrome that is closely correlated to visceral obesity, dyslipidemia, insulin resistance, and type 2 diabetes, thus suggesting that NAFLD is another feature of the metabolic syndrome. The pathophysiology of non-alcoholic fatty liver disease involves insulin resistance, which causes hepatic steatosis, a process enhanced in patients with type 2 diabetes mellitus and/or obesity.
Materials and Methods: This study was conducted inDepartment of Medicine and Department of Radiology, GMC, Kannauj. This was a Cross-sectional study done over a period of 18 months. The study include admitted patients having fatty liver finding on ultrasound and patients having any history of alcohol abuse and viral hepatitis were excluded. Sample size was 65.
Results: Prevalence of dyslipidemia was 63.4% among diabetics as compared to 16.7% among non-diabetics. Statistically, this difference was significant (p<0.001). Similarly, mean FBS and PP BS levels were also significantly higher among patientswith dyslipidemia as compared to those not having dyslipidemia (p<0.05).
Conclusion: In present study prevalence of dyslipidemia with NAFLD-diabetes mellitus in cohort was found to statistically significant (p<0.001), which emphasizes that dyslipidemia is added disadvantage to precipitate non alcoholic fatty liver disease.
Impact Factor
2022: 6.012
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