Assessment of serum electrolyte and lipid profile in hypothyroidism patients in kashmir valley india

Hypothyroidism is a frequent, potentially serious clinical entity resulting from deficiency of Thyroid hormones or due to their impaired activity which may affect electrolyte levels as well as lipids in circulation. The objective of this study was to find out the effect of hypothyroidism on certain electrolytes and on lipids. During our study among all the Thyroid patients the highest number (76.86%) of patients belonged to the female gender and majority of patients were between the age group 31-40 years. When the cases and controls were compared, there was a significant variation in some biological values between the two groups. All the lipids measured (namely total cholesterol, triglycerides, LDL and HDL) were found to be significantly elevated in hypothyroid patients when compared to the controls (p˂0.001). The levels of sodium were significantly decreased in cases when compared to controls (p˂0.001). However, serum potassium levels in hypothyroid patients were found to be less than that of controls but the difference was not significant. The serum TSH values of patients were studied in relation to the values of serum lipids, sodium and potassium. On analyzing the values, a significant positive correlation between the serum levels of TSH and lipids was noticed, while a significant negative correlation was found between serum TSH and electrolyte levels. From this study, we were able to conclude that higher the TSH levels, higher will be the level of lipids in blood while there was a decrease in the values of electrolytes (Sodium and Potassium).