Assessment of myocardial performance index of left ventricle by echo & its correlation with syntax score in acute stemi patients

Aims and Objectives
• To assess the role of Left Ventricular Myocardial Performance Index in Acute STEMI patients using both conventional Pulse Wave Doppler and Tissue Doppler Echocardiography.
• To study the complexity of coronary artery disease in Acute STEMI patients undergoing coronary angiogram by using SYNTAX score.
• To evaluate if myocardial performance index predicts Angiographic severity of coronary artery disease in STEMI patients.
• To assess the relationship between myocardial performance index and the systolic, diastolic dysfunction in acute STEMI patients.
• The Prognostic value of myocardial performance index in predicting the in-hospital morbidity
Methods
• Hospital - based observational study of 150 Patients who were admitted to ICCU, thrombolysed for first episode of acute STEMI were included.
Results
• MPI is significantly higher in anterior MI than in Inferior MI patients(0.59 ±0.07 0.51 ±0.06, p= 0.001).
• The myocardial performance index is significantly elevated in Triple Vessel Disease compared to Double Vessel Disease and Single Vessel Disease. (MPI- TD: 0.64 ± 0.075 vs. 0.53 ± 0.068, p= 0.001)
Conclusions
SYNTAX score has high positive correlation with MPI derived by conventional Pulsed Wave Doppler and Tissue Doppler method. So the Left ventricular MPI apart from assessing overall LV function can help in predicting severity of coronary artery disease. Tei index has good correlation with Ejection Fraction which is the most commonly used parameters for predicting outcomes in Myocardial infarction patients. Thus the MPI/Tei index which combines the systolic and diastolic myocardial performance is easily to obtain at the patient’s bedside, a useful noninvasive method to predict clinical outcome, severity of coronary artery disease in patients with acute myocardial infarction