Introduction: “Hepatitis” means inflammation of the liver. The liver is a vital organ that processes nutrients, filters the blood, and fights infections. When the liver is inflamed or damaged, its function can be affected. Heavy alcohol use, toxins, some medications, and certain medical conditions can cause hepatitis. However, hepatitis is most often caused by a virus. Acute viral hepatitis (AVH) continues to be a major public health burden in developing countries like India. In the present study, we assessed correlation between clinical presentation of acute viral hepatitis and alterations in serum lipoprotein levels.
Materials and Methods: It was a case control analytical study, conducted among 30 presumptive cases of acute viral hepatitis, admitted under department of general medicine, KIMS, Karad during the period of October 2015 to March 2017.
Results: In this study, different mean parameters of lipid profile in cases and controls as well as differences were calculated and compared to each other. Mean total cholesterol was 169.700 ± 33.225 and mean HDL was 25.10 ± 3.467. Both were significantly lower (p < 0.05) in cases than controls.
Conclusions: Lipid parameters (particularly HDL) are deranged in acute viral hepatitis as compared to controls, more deranged during acute phases of viral hepatitis than recovering phases and in complicated cases as compared to uncomplicated cases, so we can use serum lipid profile as prognostic marker in acute viral hepatitis.
Impact Factor
2022: 6.012
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