Objective: The objective of this study was to find the efficiency of extract of Pletranthus ambonicus when tested on selected oral microbes.
Methods: The investigation was done by Agar well diffusion method.
Result: Plectranthus ambonicus has antibacterial activity against Streptococcus mutans showing a zone of inhibition of 27mm, which is the major initiator of dental caries. It also has inhibitory effect against Enterococcus faecalis and Lactobacillus acidophilus.
Conclusion: The extract Plectranthus ambonicus showed a significant antibacterial activity. Detailed study on pharmacological activities such as anti inflammatory study and others on this plant is needed for future health care product formulations like mouthwashes and toothpastes.